Margaret Tackitt, of St. Charles, Missouri, died on Monday, January 30, 2012 at the age of 82. Loving wife of the late James F. Tackitt; dear daughter of the late Edward and Margaret M. Amsinger; devoted mother of Margaret (Gerald) Brennan, Michele (Don) Floyd, Jacquline (Christopher) Pagoria, and Keith (Jamie) Tackitt; cherished grandmother of Kelly (David) Kendrick, Patrick (Ann) Brennan, Lisa (Eric) Schwan, Rabecca (Eric) Davis, Christopher J. Pagoria, and Madison Tackitt; prized great-grandmother of Tyler, Alyssa, Kyle, Gavin, Addysen, and Samantha; dear sister of Shirley (Jack) Becker; and a beloved aunt, cousin and friend to many. In lieu of flowers, memorials may be made to Autism Speaks, 1060 State Road 2nd Floor, Princeton, NJ 08540.